![]() The SAG is arguably the most used biochemical calculation in nephrology. ![]() Serum Anion Gap (SAG) (in mEq/L) = Na – (Cl + HCO3). This matchup sees the heavyweight serum AG go up against its lesser-known rival, the urine AG. (3) Serum Anion Gap versus (6) Urine Anion GapĪnion Gap (AG): the difference between the measured cations (positively charged ions) and the measured anions (negatively charged ions) can be very helpful in acid/base disorders. ![]() Despite being a young squad, the big-money Team Vaptan have the swagger of conference veterans and will be confident of a successful run to the latter stages of this year’s NephMadness tournament. If this is a concern, some clinicians (including this one) have started at a lower than licensed dose, 7.5 mg daily. Hypertonic saline is particularly indicated in cases of moderate to severely symptomatic hyponatremia (eg, seizures), usually acute but also severe chronic (Na 12mEq/L/day (now suggested ≤ 10 mEq/L and ≤ 8 mEq/L for patients at high risk). leading to a net retention of 0.5 L – 0.35 L = 0.15 L or 150 mL of free water, exacerbating hyponatremia!
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